Blood is essential to life; we cannot live without it. Blood is not what gives life, but it is a necessary part of it. When saying life is in the blood, Leviticus 17 warned against pagan rituals of draining and eating blood, which were both idolatrous and showed disrespect for the sanctity of life (cf. Genesis 9:3–6).
Because life and blood are closely related, God used blood sacrifices to deal with sin by killing one life (an animal) in place of another (the sinning human). Thus, God gave animal blood to make atonement for human souls (Leviticus 17:11). This demonstrates that sin requires death, but that forgiveness can come through a substitute.
However, because an animal is not a human, no animal death completely removes human sin (Hebrews 10:4). This is why Jesus came and died. By taking on humanity (Philippians 2:7–8), He became like us in every way except without sin (Hebrews 4:15). Since only sinners must die (Romans 6:23), He did not need to die—but did so willingly to give His life, His blood, as a sacrifice for all who believe in Him.
Life being in the blood has profound implications. It means that one life can be given in the place of another. That is, one’s blood can be shed for another. From the beginning, Scripture teaches that God requires the death of anyone who sins. However, it also showed that forgiveness was available through the death of another life. Every animal sacrificed in the Old Testament was a picture of this truth. However, since they offered limited forgiveness, being only animals, they were not of sufficient value to completely atone for human sin. Instead, they pointed forward to the need for a better sacrifice, one that was valuable enough to pay for human sin.
This is why Jesus came. Being fully God, He never sinned. Being fully human, He could die and fully pay for human sin. Thus, when He died on the cross, He did so to take our place. He endured the death we deserved so that we could receive the life He offers. His resurrection proved that the debt was fully paid and that death no longer has power over those who belong to Him. The blood of Jesus was the very means by which God brings forgiveness, peace, and eternal life.
If you have never trusted in Christ, this is the good news: your sin can be forgiven, and you can be made new. God offers this gift freely, not because of what you can do, but because of what Jesus has already done. To receive it, you must repent of your sin and believe that His death and resurrection are enough to save you. When you do, God gives you new life and fills you with His Spirit so that you can walk with Him now and live with Him forever.