The ego is our sense of self; it represents the "I" aspect of a person. Though it is not inherently prideful, it can easily represent human pride because our natural tendency as humans is to be self-focused. The Bible doesn't discuss the ego by name; however, it gives us guidelines to live by that often conflict with our natural egos. Throughout the Bible, an inflated sense of self is shown to be destructive, as seen beginning with Lucifer. God calls us to love Him and love others. We cannot do this when we have a conflated view of self. Instead, we are called to live humbly and recognize who we are before Christ. Doing this allows us to live as Christ did and to glorify Him in all we do.
The Bible calls us to live with humility. We can do this when we see ourselves rightly before God and rightly among others (Romans 12:3). Jesus serves as the best example of humility. Jesus did only what His Father God directed Him to do: "I can do nothing on my own. As I hear, I judge, and my judgment is just, because I seek not my own will but the will of him who sent me" (John 5:30). Jesus recognized that even talent and spiritual revelation are gifts from God (John 7:16). By coming to earth as a human, Jesus "emptied himself, by taking the form of a servant, being born in the likeness of men." (Philippians 2:7). Living in humility like Jesus brings rest to our minds (Matthew 11:29).
The true purpose of humility is that it enables us to honor God and to treat others as better than ourselves: "Do nothing from selfish ambition or conceit, but in humility count others more significant than yourselves. Let each of you look not only to his own interests, but also to the interests of others" (Philippians 2:3–4). The greatest commandments God has given us are to love Him with all of our heart, soul, and mind and to love others as we love ourselves (Matthew 22:37–40; John 15:1–17). There is not room to fulfill these commands if we allow our egos to have first place in our lives.