A Mudra is a symbolic hand gesture used in Hindu and Buddhist ceremonies and statuary, and in Indian dance. Eastern teachings such as meditation and yoga are popular and many Christians worldwide today have some involvement in Hindu and/or Buddhism through the practice of yoga. There is a wide variety of meanings within the various gestures using both the hands and the body itself. The purpose of a Mudra is to deepen a person's spiritual life and redirect their energy. The religions that use Mudras are based upon false gods, not the True and the Living Creator God of the universe. They are also based upon the use of superstitious hand gestures that cannot bring you into any right relationship with God but might even attract spirits that will lead you away from God. The gods of these religions are not gods at all (Acts 19:26), but the meanings behind the hand signs generate worship or spiritual involvement related to those pagan gods.
Many Christians have promoted the practice of "holy yoga" which "Christianizes" the pagan practice. Besides the fact that the mudras may attract pagan spirits into your life, they may also cause others to stumble into Hinduism or Buddhism as they watch your use of such gestures and practices.
We should be careful not to do practices or participate in things that are not honoring to God, and we should also be careful that we do not use our Christian liberties to cause a brother to stumble (1 Corinthians 8).
The bottom line is that Mudras and yoga do not "align" with Christ at all and must be avoided. The posture of the Christian's worship, including the way we live our lives, must be a contrite and humble heart (Psalm 51:17).
The Christian life is not enhanced by borrowed rituals or mystical gestures but transformed by a renewed mind that leads to a life that lives according to God's ways. Scripture calls us to flee idolatry, pursue holiness, and love others enough not to blur spiritual lines that God has made clear. True worship is not about postures of the body but posture of the soul—a contrite heart, surrendered fully to Christ, refusing substitutes and reflecting Christ with undivided devotion.